When it comes to raising blood cholesterol, eggs have gotten a bad reputation. Over the
years, doctors have warned that eating too many may have a negative impact on
heart health, but research along the way has been mixed.
Yes, one study linked eating three or four eggs per week with a 6 percent increase in the risk of cardiovascular disease.
But other studies have concluded that consuming up to seven eggs a week is not associated with heart disease in healthy people.
Now a study to be presented at the American College of Cardiology's Annual Scientific Sessions in Atlanta in April supports the claim that eggs — specifically, fortified eggs from hens fed nutrient-enriched feed — may not be harmful.
The modest-sized study, led by scientists at Duke University
in Durham, North Carolina, found that over a four-month period, people eating a
dozen fortified eggs each week had the same blood cholesterol levels as people
eating no more than two eggs of any kind per week.
Why the Focus on Fortified Eggs?
“We wanted to add some solid evidence on the effects of
fortified eggs, especially because nonfortified eggs have been a subject for
investigation for many years,” says Nina
Nouhravesh, MD, a study author and research fellow at the Duke Clinical
Research Institute.
Fortified eggs, she noted, may be healthier than regular
eggs because they offer extra amounts of vitamins D, B, and E, omega
fatty acids, and iodine, along with less saturated
fat.
Study Included People With or at Risk for Heart Disease
Dr. Nouhravesh and her team followed 140 adults, all 50 and
older (average age 66), who’d had at least one cardiac event in the past, such
as heart attack, or had risk factors for cardiovascular
disease such as high blood pressure, high cholesterol, increased body
mass index (BMI), or diabetes. Half were female; 27 percent were Black.
Over four months, half the subjects were directed to eat 12
fortified eggs per week while the other half were required to eat up to two
eggs (fortified or not). Fortified eggs come from hens given special feed that
is rich in vitamins and minerals.
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At the end of the study period, the researchers found that
differences between the two groups in levels of HDL
“good” cholesterol and LDL
“bad” cholesterol weren’t statistically significant.
The researchers noted that participants in the fortified egg
group actually had slightly lower levels of HDL and LDL: 0.64 milligrams per
decliter (mg/dL) in HDL and 3.14 mg/dL in LDL.
Patients Want to Know, Are Eggs Bad for My Heart?
“I treat a lot of patients for cholesterol, so the egg issue
comes up frequently,” says Parveen Garg, MD, a cardiologist with Keck
Medicine of USC in Los Angeles. “I think what’s interesting about this
study is that it shows eating fortified eggs doesn’t really adversely affect
your cholesterol.”
Dr. Garg, who was not involved in this study, recognizes that eggs contain a high amount of dietary cholesterol: One large egg has about 200 mg, all in the yolk.
“There’s sufficient evidence, however, to question the whole
idea that the more cholesterol you have in your diet, the more is going to show
up in your blood levels,” says Garg, who emphasizes that dietary cholesterol is
different from blood cholesterol.
He notes that saturated fat is more likely to impact blood
cholesterol, adding that eggs are low in saturated fat compared with foods like
red meat and dairy.
Study Limitations and More Research Ahead
Nouhravesh stresses that as a pilot study, her research has
several limitations. While participants provided some information regarding
dietary intake showing similarities in the two groups (including daily
calories, proteins, and saturated fat), specifics were lacking.
Plus, the study did not take into account egg preparation:
Some subjects might have fried their eggs in butter, increasing saturated fat,
while others may have simply boiled them.
The research also did not take into account the subjects’
exercise regimens or medications, both which could be influencing factors.
The study was funded by Eggland’s Best, a company that makes
and sells fortified eggs. Whether the results of this trial correspond to
nonfortified eggs is unknown.
Nouhravesh suggests that some findings of the study warrant
further exploration. “In the current trial we found a potential benefit [of
fortified eggs] on cholesterol levels in patients who were older and in
patients with diabetes, which we think is very exciting data which should be
further investigated in larger trials,” she says.
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